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Prague had been under siege for several days since the chemical attacks across Europe, with the Russian Army brutally crushing dissent and oppressing most of the population. Kamarov, who possibly deserted from the Russian Army, had a hand in organizing a small rebel group, and was contacted by Captain John Price, who informed them of Vladimir Makarov's presence and the Loyalist, Czech Resistance, and the disavowed TF141 plan to assassinate him.
To that end, an uprising was staged to cover Price's, John "Soap" MacTavish's, and Yuri's movement into position. As Price and Kamarov cleared snipers on the rooftops, Soap and Yuri quietly cleared out some Russian soldiers on the ground. When the two teams linked up, Czech Resistance fighters poured out into the streets to battle the Russians, while the assassination squad made it to their respective positions.
Price set himself up on the tower of the Hotel Lustig, while Soap and Yuri remained at their nest in a church across from the hotel, and Kamarov would be inside the hotel. The assassination goes awry, killing Kamarov and mortally wounding MacTavish, opening up his recently closed wounds when General Shepherd stabbed him and Yuri and Price alternated in carrying him to the rebel base, where Soap bleeds out and dies, but not before disclosing the revelation about Yuri. When the pursuing Russian forces arrive, Price and Yuri are hurried out and have a confrontation, and the rebels makes a stand with unknown results.
It is unknown what happens after MacTavish's death, and nothing is hinted at, although it is likely that heavy casualties were sustained by the Czech Resistance. Price and Yuri went on to kill Makarov and avenge both of their fallen friends.
After Ultranationalist Russia and the United States signed a peace treaty, Russian forces withdrew from Czech Republic leaving it in complete ruins.